| Coaches | |
|---|---|
| Position | Name |
| Head Coach | Jim Harbaugh |
| Offensive Coordinator | Greg Roman |
| Defensive Coordinator | Jesse Minter |
| Special Teams Coach | Ryan Ficken |
| Offense | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| POS | NO | Player 1 | NO | Player 2 | NO | Player 3 | NO | Player 4 | NO | Player 5 |
| FB | 44 | Ben Mason | ||||||||
| QB | 10 | Justin Herbert | 2 | Easton Stick | 8 | Max Duggan | 16 | Casey Bauman(R) | ||
| RB | 4 | Gus Edwards | 27 | J.K. Dobbins | 30 | Kimani Vidal(R) | 28 | Isaiah Spiller | 42 | Elijah Dotson |
| TE | 81 | Will Dissly | 88 | Hayden Hurst | 89 | Donald Parham Jr. | 84 | Stone Smartt | 49 | Zach Heins(R) |
| WR | 5 | Joshua Palmer | 1 | Quentin Johnston | 15 | Ladd McConkey | 9 | DJ Chark Jr. | 12 | Derius Davis |
| Defense | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| POS | NO | Player 1 | NO | Player 2 | NO | Player 3 | NO | Player 4 | NO | Player 5 |
| FS | 32 | Alohi Gilman | 22 | JT Woods | 46 | Akeem Dent(R) | ||||
| LCB | 26 | Asante Samuel Jr. | 36 | Ja'Sir Taylor | 33 | Deane Leonard | 23 | Matt Hankins | 40 | Robert Kennedy |
| LDE | 56 | Morgan Fox | 99 | Scott Matlock | 54 | Savion Jackson(R) | ||||
| LILB | 25 | Junior Colson(R) | 31 | Nick Niemann | 43 | Troy Dye | 50 | Shane Lee | ||
| NT | 93 | Otito Ogbonnia | 91 | Christopher Hinton | 72 | Jerrod Clark | ||||
| RCB | 7 | Kristian Fulton | 20 | Cam Hart(R) | 38 | Chris Wilcox | ||||
| RDE | 95 | Poona Ford | 98 | Justin Eboigbe | NA | Chris Okoye | ||||
| RILB | 6 | Denzel Perryman | 25 | Junior Colson(R) | 51 | Jeremiah Jean-Baptiste(R) | ||||
| SLB | 52 | Khalil Mack | 48 | Bud Dupree | 94 | Chris Rumph II | NA | Justin Hollins | 92 | Andrew Farmer II |
| SS | 3 | Derwin James Jr. | 24 | AJ Finley | 35 | Jalyn Phillips | 37 | Thomas Harper(R) | ||
| WLB | 97 | Joey Bosa | 45 | Tuli Tuipulotu | 59 | Ty Shelby | 92 | Andrew Farmer II | 57 | Tre'Mon Morris-Brash(R) |
| Special Teams | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| POS | NO | Player 1 | NO | Player 2 | NO | Player 3 | ||||
| K | 11 | Cameron Dicker | ||||||||
| KR | 12 | Derius Davis | 82 | Brenden Rice(R) | ||||||
| P | 16 | JK Scott | ||||||||
| PR | 12 | Derius Davis | 15 | Ladd McConkey | ||||||
